Education&ScienceWebinars

Management of Respiratory Infections: Advancing The Integration of Diagnostic Stewardship and Infection Prevention

Wednesday 11 December 2024

  • 12:00 - 13:30 India time (UTC+ 5:30)
  • 14:30 – 16:00 Singapore, Hong Kong time (UTC+8)
  • 15:30 – 17:00 Tokyo time (UTC+9)

An educational initiative supported by Cepheid

This webinar has ended.

OUTLINE

Join us for an engaging webinar on Management of Respiratory Infections: Advancing The Integration of Diagnostic Stewardship and Infection Prevention. This educational initiative, brought to you by APSR and supported by Cepheid, offers a unique opportunity to interact with esteemed speakers and panelists.

FORMAT

  1. Welcome and Introduction from the APSR
  2. Presentation-1 (20 mins)
  3. Presentation-2(20 mins)
  4. Panel Discussion (30 mins)
  5. Q&A (15 mins)
  6. Closing Remarks (5 mins)

TOPICS

Talks
”Rapid multiplex PCR for respiratory tract infections after COVID-19 pandemic” – Dr Bone Tang

“Diagnostic Approaches for Enhanced Treatment and Prevention Strategies of Respiratory Infections” – Dr Takeshi Tanaka

Panel Discussion
“Management of Respiratory Infections – Unlocking clinical, operational, and economic efficiencies in an evolving respiratory landscape”

SPEAKERS & PANELISTS

Dr Bone Tang

SPEAKER

Honorary Consultant in Microbiology
Hong Kong Sanatorium and Hospital

Hong Kong

Dr Takeshi Tanaka

SPEAKER

Hospital Associate Professor
Infection Control and Education Center
Nagasaki University Hospital
Nagasaki University School of Tropical Medicine and Global Health

Japan

Dr Masafumi Seki

PANELIST

Professor
Division of Infectious Diseases and Infection Control, Saitama Medical University International Medical Center

Japan

Dr Ranganathan N Iyer

PANELIST

Consultant Clinical Microbiology, ID and Infection Control
Rainbow Hospital for Women and Children
Hyderabad

India

Dr Chieh-Liang Wu

MODERATOR

Head of Respiratory Infections (non-tuberculous) Assembly
APSR

Taiwan

Dr Romy Ho

MODERATOR

Director
Medical Affairs, SEAK and Japan
Cepheid

Singapore

Dr Yoshinori Hasegawa

CLOSING REMARKS

President-Elect
APSR

Japan

Questions for panelists and their responses

What does panel suggest , should one totally rely on multiplex panel report or it should be interpreted in conjunction with culture report especially for bacterial pathogens

Dr Bone Tang responds:

No. We should NOT totally rely on the multiplex PCR as it cannot replace the culture and sensitivity. Multiplex PCR is not all encompassing and the included genetic resistance markers may not predict all the antibiotic resistance phenotypes. Therefore it can only be complementary to the culture and sensitivity.

Dr Takeshi Tanaka responds:

For bacterial infections, it is generally recommended to combine culture testing with conventional methods in the context of antimicrobial resistance (AMR). This approach is essential for planning treatment strategies based on drug MIC results obtained from cultures, ensuring the appropriate use of antimicrobial agents.

Dr Iyer Ranganathan N responds:

Any Multiplex PCR report must be interpreted in the light of the clinical details of the patient and if available the details of the cultures performed on respiratory specimens in Microbiology laboratory. Sole reliance on Multiplex PCR panels could be disastrous

I was wondering, from a clinical perspective, how important is it to detect viruses that do not have specific treatments, including RSV?

Dr Bone Tang responds:

It is important because we want to establish the diagnosis. At least we would like to know the etiology of the clinical presentation which can be very similar to other diagnosis such as autoimmune diseases and drug induced pneumonitis which sometimes rely heavily by exclusion of the other causes. Secondly, it is also important for epidemiology and public health perspectives. Moreover, non specific measures such as Immunoglobulin may be useful in viral pneumonitis.

Dr Takeshi Tanaka responds:

The significance of detecting viral infections for which there is no cure lies in the understanding that if the virus is with severe disease, compreh its epidemiological background becomes useful. Additionally, it is crucial to the status of viral infections, they are often complicated by secondary bacterial infections following viral infections.

Dr Iyer Ranganathan N responds:

It is still important to detect all viral infections ( irrespective of whether they have a specific anti- viral agent ) as this helps diagnose a clinical condition. Moreover many of the viral Respiratory tract infections do have a specific anti- viral agent / salvage therapy in severe cases in the ICU. We have been able to manage many RSV infections with Ribavirin and Adenoviral respiratory infections ( severe cases ) with Cidofovir when other forms of management don’t work.

Many studies have shown the high frequency of Rhinovirus in upper/lower RTIs. Is there a need to include RV in these surveillance panels in the future?

Dr Bone Tang responds:

Yes, definitely. Some Enterovirus such as EV-D68 can cause severe LRTI and therefore it would be advisable to include RV/ EV in the PCR.

Dr Takeshi Tanaka responds:

I think this approach will become more desirable in the future.

Dr Iyer Ranganathan N responds:

It may be optional to include Rhinovirus in Lower respiratory tract panels. However they are an important cause of Upper respiratory tract infections and may be important for inclusion in Upper tract panels