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Educational Articles
Hypoxic indices for obstructive sleep apnoea severity and cardiovascular disease risk prediction: A comparison and application in a community population
September 2024
Author: Xinjie Hui, Wenhao Cao, Zeyu Xu, Junwei Guo, Jinmei Luo, Yi Xiao
Comment by Mark Lavercombe: The association between obstructive sleep apnoea and cardiovascular risk is well established, however common metrics such as apnoea-hypopnoea index (AHI) and oxygen desaturation index (ODI) don’t fully explain the association. In this study using data for 5804 participants from the Sleep Heart Health Study, a series of hypoxic indices are evaluated for their predictive accuracy and concordance for cardiovascular morbidity and mortality outcomes. The Sleep Breathing Impairment Index (SBII) and proportion of sleep time with the duration of respiratory events causing desaturation (pRED_3p) metrics performed best for predicting the risk of CVD mortality and morbidity in OSA patients, respectively.
Medical Education Editor for Respirology
Dr Mark Lavercombe was appointed in this specialist editor role in 2021 to further expand and strengthen Respirology’s contribution to medical education.
Located in Melbourne, Australia, he works as a clinician in respiratory health and sleep disorders at Western Health and is affiliated with The University of Melbourne as a distinguished expert in medical education.
He became a member of our Editorial Board in 2016 with the responsibility of selecting new Respirology publications with educational value, which has grown into a curated article selection featured on this page, as a benefit to APSR members.
Dr Lavercombe also authors a column in Respirology on his most recent choices and their specific value to continued medical education for our readers around the world.
